Christine Hsieh, PhD

Assistant Professor, Department of Medicine, Division of Rheumatology
M_MED-VAMC-RHEU
hsiehlab.ucsf.edu

Dr. Christine Hsieh is a cellular neuroimmunologist focused on understanding mechanisms of inflammation that contribute to diseases with an urgent need for therapies, such as lupus, frontotemporal dementia (FTD) and traumatic brain injury (TBI). Her research has largely focused on the roles of innate immune receptors expressed by macrophages, microglia, B cells, and/or NK cells in disease, and how receptor activity can be modulated for therapy.

Publications

ADAM17 Is The Main Sheddase For The Generation Of Human Triggering Receptor Expressed In Myeloid Cells (hTREM2) Ectodomain And Cleaves TREM2 After Histidine 157.

bioRxiv

Dominik Feuerbach, Patrick Schindler, Carmen Barske, Stefanie Joller, Edwige Beng-Louka, Katie A. Worringer, Sravya Kommineni, Ajamete Kaykas, Daniel J. Ho, Chaoyang Ye, Karl Welzenbach, Gaelle Elain, Laurent Klein, Irena Brzak, Anis K. Mir, Christopher J. Faraday, Reiner Aichholz, Simone Popp, Nathalie George, Christine L. Hsieh, Mary C. Nakamura, Ulf Neumann