Also visit https://hsiehlab.ucsf.edu/

 

The Effect of Type 2 Diabetes on CD36 Expression and the Uptake of OxLDL. 

Kanoke A, Nishijima Y, Ljungberg M, Omodaka S, Yang SY, Wong S, Rabillera G, Tominagac T, Hsieh CL, Liu J.

Experimental Neurology, 2020 Sept; 334: 113461.  Epub 2020 Sept 17.

Age-related changes to macrophages are detrimental to fracture healing in mice.

Clark D, Brazina S, Yang F, Hu D, Hsieh CL, Niemi EC, Miclau T, Nakamura MC, Marcucio R.  

Aging Cell, 2020 Mar; 19(3): e13112.  Epub 2020 Feb 25.  PubMed PMID: 32096907; PubMed Central PMCID: PMC7059136.

Heterogeneity in HIV and cellular transcription profiles in cell line models of latent and productive infection: implications for HIV latency.

Telwatte S, Morón-López S, Aran D, Kim P, Hsieh C, Joshi S, Montano M, Greene WC, Butte AJ, Wong JK, Yukl SA.  

Retrovirology. 2019 Nov 11;16(1):32. doi: 10.1186/s12977-019-0494-x. PubMed PMID: 31711503; PubMed Central PMCID: PMC6849327.

Triggering receptor expressed on myeloid cells-2 expression in the brain is required for maximal phagocytic activity and improved neurological outcomes following experimental stroke.

Kurisu K, Zheng Z, Kim JY, Shi J, Kanoke A, Liu J, Hsieh CL, Yenari MA.  

J Cerebral Blood Flow Metabolism. 2019 Oct;39(10):1906-1918. doi: 10.1177/0271678X18817282. Epub 2018 Dec 7. PubMed PMID: 30523715; PubMed Central PMCID: PMC6775587.

Galectin-3, a novel endogenous TREM2 ligand, detrimentally regulates inflammatory response in Alzheimer's disease.

Boza-Serrano A, Ruiz R, Sanchez-Varo R, García-Revilla J, Yang Y, Jimenez-Ferrer I, Paulus A, Wennström M, Vilalta A, Allendorf D, Davila JC, Stegmayr J, Jiménez S, Roca-Ceballos MA, Navarro-Garrido V, Swanberg M, Hsieh CL, Real LM, Englund E, Linse S, Leffler H, Nilsson UJ, Brown GC, Gutierrez A, Vitorica J, Venero JL, Deierborg T.  

Acta Neuropathol. 2019 Aug;138(2):251-273. doi: 10.1007/s00401-019-02013-z. Epub 2019 Apr 20. PubMed PMID: 31006066; PubMed Central PMCID: PMC6660511.

MicroRNA-383 located in frequently deleted chromosomal locus 8p22 regulates CD44 in prostate cancer.

Bucay N, Sekhon K, Yang T, Majid S, Shahryari V, Hsieh C, Mitsui Y, Deng G, Tabatabai ZL, Yamamura S, Calin GA, Dahiya R, Tanaka Y, Saini S.  

Oncogene. 2017 May 11;36(19):2667-2679. doi: 10.1038/onc.2016.419. Epub 2016 Nov 28. PubMed PMID: 27893706; PubMed Central PMCID: PMC5426972.

Brain trauma elicits non-canonical macrophage activation states.

Kim CC, Nakamura MC, Hsieh CL.  

J Neuroinflammation. 2016 May 24;13(1):117. doi: 10.1186/s12974-016-0581-z. PubMed PMID: 27220367; PubMed Central PMCID: PMC4879757.

Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation. 

Lui H, Zhang J, Makinson SR, Cahill MK, Kelley KW, Huang HY, Shang Y, Oldham MC, Martens LH, Gao F, Coppola G, Sloan SA, Hsieh CL, Kim CC, Bigio EH, Weintraub S, Mesulam MM, Rademakers R, Mackenzie IR, Seeley WW, Karydas A, Miller BL, Borroni B, Ghidoni R, Farese RV Jr, Paz JT, Barres BA, Huang EJ. 

Cell. 2016 May 5;165(4):921-35. doi: 10.1016/j.cell.2016.04.001. Epub 2016 Apr 21. PubMed PMID: 27114033; PubMed Central PMCID: PMC4860138.

Triggering receptor expressed on myeloid cells 2 (TREM2) deficiency attenuates phagocytic activities of microglia and exacerbates ischemic damage in experimental stroke.

Kawabori M, Kacimi R, Kauppinen T, Calosing C, Kim JY, Hsieh CL, Nakamura MC, Yenari MA.  

J Neuroscience. 2015 Feb 25;35(8):3384-96. doi: 10.1523/JNEUROSCI.2620-14.2015. PubMed PMID: 25716838; PubMed Central PMCID: PMC4339351.

CCR2 deficiency impairs macrophage infiltration and improves cognitive function after traumatic brain injury. 

Hsieh CL, Niemi EC, Wang SH, Lee CC, Bingham D, Zhang J, Cozen ML, Charo I, Huang EJ, Liu J, Nakamura MC. 

J Neurotrauma. 2014 Oct 15;31(20):1677-88. doi: 10.1089/neu.2013.3252. Epub 2014 Jul 21. PubMed PMID: 24806994; PubMed Central PMCID: PMC4545982.

Triggering Receptor Expressed on Myeloid Cells-2 Correlates to Hypothermic Neuroprotection in Ischemic Stroke. 

Kawabori M, Hokari M, Zheng Z, Kim JY, Calosing C, Hsieh CL, Nakamura MC, Yenari MA. 

Therapeutic Hypothermia Temperature Management. 2013 Dec 1;3(4):189-198. doi: 10.1089/ther.2013.0020. PubMed PMID: 24380032; PubMed Central PMCID: PMC3868297.

Traumatic brain injury induces macrophage subsets in the brain.

Hsieh CL, Kim CC, Ryba BE, Niemi EC, Bando JK, Locksley RM, Liu J, Nakamura MC, Seaman WE.  

Eur J Immunology. 2013 Aug;43(8):2010-22. doi: 10.1002/eji.201243084. Epub 2013 Jun 5. PubMed PMID: 23630120; PubMed Central PMCID: PMC4210355.

A role for TREM2 ligands in the phagocytosis of apoptotic neuronal cells by microglia.

Hsieh CL, Koike M, Spusta SC, Niemi EC, Yenari M, Nakamura MC, Seaman WE.  

J Neurochemistry. 2009 May;109(4):1144-56. doi: 10.1111/j.1471-4159.2009.06042.x. Epub 2009 Mar 19. PubMed PMID: 19302484; PubMed Central PMCID: PMC3087597.

NKp30 is a functional activation receptor on a subset of rat natural killer cells.

Hsieh CL, Nagasaki K, Martinez OM, Krams SM.  

European J Immunology. 2006 Aug;36(8):2170-80. doi: 10.1002/eji.200635982. PubMed PMID: 16821237; PubMed Central PMCID: PMC4084722.

IFN-gamma, produced by NK cells that infiltrate liver allografts early after transplantation, links the innate and adaptive immune responses.

Obara H, Nagasaki K, Hsieh CL, Ogura Y, Esquivel CO, Martinez OM, Krams SM.  

American J Transplantation. 2005 Sep;5(9):2094-103. doi: 10.1111/j.1600-6143.2005.00995.x. PubMed PMID: 16095488; PubMed Central PMCID: PMC1473982.

Identification, cloning, and characterization of a novel rat natural killer receptor, RNKP30: a molecule expressed in liver allografts.

Hsieh CL, Ogura Y, Obara H, Ali UA, Rodriguez GM, Nepomuceno RR, Martinez OM, Krams SM.  

Transplantation. 2004 Jan 15;77(1):121-8. doi: 10.1097/01.TP.0000110423.27977.6F. PubMed PMID: 14724446.

Targeted gene replacement of a ferredoxin gene in Trichomonas vaginalis does not lead to metronidazole resistance.

Land KM, Delgadillo-Correa MG, Tachezy J, Vanacova S, Hsieh CL, Sutak R, Johnson PJ.  

Molecular Microbiology. 2004 Jan;51(1):115-22. doi: 10.1046/j.1365-2958.2003.03791.x. PubMed PMID: 14651615.

Unprocessed Toxoplasma ROP1 is effectively targeted and secreted into the nascent parasitophorous vacuole.

Bradley PJ, Hsieh CL, Boothroyd JC.  

Molecular Biochemical Parasitology. 2002 Nov-Dec;125(1-2):189-93. doi: 10.1016/s0166-6851(02)00162-7. PubMed PMID: 12467986.

NK cells and transplantation.

Hsieh CL, Obara H, Ogura Y, Martinez OM, Krams SM.  

Transplant Immunology. 2002 May;9(2-4):111-4. doi: 10.1016/s0966-3274(02)00033-3. Review. PubMed PMID: 12180816.